Motoric Cognitive Risk Syndrome: Multicountry Prevalence and Dementia Risk

OBJECTIVES: Our objective is to report prevalence of motoric cognitive risk syndrome (MCR), a newly described predementia syndrome characterized by slow gait and cognitive complaints, in multiple countries, and its association with dementia risk. METHODS: Pooled MCR prevalence analysis of individual data from 26,802 adults without dementia and disability aged 60 years and older from 22 cohorts from 17 countries. We also examined risk of incident cognitive impairment (Mini-Mental State Examination decline ≥4 points) and dementia associated with MCR in 4,812 individuals without dementia with baseline Mini-Mental State Examination scores ≥25 from 4 prospective cohort studies using Cox models adjusted for potential confounders. RESULTS: At baseline, 2,808 of the 26,802 participants met MCR criteria. Pooled MCR prevalence was 9.7% (95% confidence interval [CI] 8.2%-11.2%). MCR prevalence was higher with older age but there were no sex differences. MCR predicted risk of developing incident cognitive impairment in the pooled sample (adjusted hazard ratio [aHR] 2.0, 95% CI 1.7-2.4); aHRs were 1.5 to 2.7 in the individual cohorts. MCR also predicted dementia in the pooled sample (aHR 1.9, 95% CI 1.5-2.3). The results persisted even after excluding participants with possible cognitive impairment, accounting for early dementia, and diagnostic overlap with other predementia syndromes. CONCLUSION: MCR is common in older adults, and is a strong and early risk factor for cognitive decline. This clinical approach can be easily applied to identify high-risk seniors in a wide variety of settings

Off-line evaluation of indoor positioning systems in different scenarios: the experiences from IPIN 2020 competition

Every year, for ten years now, the IPIN competition has aimed at evaluating real-world indoor localisation systems by testing them in a realistic environment, with realistic movement, using the EvAAL framework. The competition provided a unique overview of the state-of-the-art of systems, technologies, and methods for indoor positioning and navigation purposes. Through fair comparison of the performance achieved by each system, the competition was able to identify the most promising approaches and to pinpoint the most critical working conditions. In 2020, the competition included 5 diverse off-site off-site Tracks, each resembling real use cases and challenges for indoor positioning. The results in terms of participation and accuracy of the proposed systems have been encouraging. The best performing competitors obtained a third quartile of error of 1 m for the Smartphone Track and 0.5 m for the Foot-mounted IMU Track. While not running on physical systems, but only as algorithms, these results represent impressive achievements.Track 3 organizers were supported by the European Union’s Horizon 2020 Research and Innovation programme under the Marie Skłodowska Curie Grant 813278 (A-WEAR: A network for dynamic WEarable Applications with pRivacy constraints), MICROCEBUS (MICINN, ref. RTI2018-095168-B-C55, MCIU/AEI/FEDER UE), INSIGNIA (MICINN ref. PTQ2018-009981), and REPNIN+ (MICINN, ref. TEC2017-90808-REDT). We would like to thanks the UJI’s Library managers and employees for their support while collecting the required datasets for Track 3. Track 5 organizers were supported by JST-OPERA Program, Japan, under Grant JPMJOP1612. Track 7 organizers were supported by the Bavarian Ministry for Economic Affairs, Infrastructure, Transport and Technology through the Center for Analytics-Data-Applications (ADA-Center) within the framework of “BAYERN DIGITAL II. ” Team UMinho (Track 3) was supported by FCT—Fundação para a Ciência e Tecnologia within the R&D Units Project Scope under Grant UIDB/00319/2020, and the Ph.D. Fellowship under Grant PD/BD/137401/2018. Team YAI (Track 3) was supported by the Ministry of Science and Technology (MOST) of Taiwan under Grant MOST 109-2221-E-197-026. Team Indora (Track 3) was supported in part by the Slovak Grant Agency, Ministry of Education and Academy of Science, Slovakia, under Grant 1/0177/21, and in part by the Slovak Research and Development Agency under Contract APVV-15-0091. Team TJU (Track 3) was supported in part by the National Natural Science Foundation of China under Grant 61771338 and in part by the Tianjin Research Funding under Grant 18ZXRHSY00190. Team Next-Newbie Reckoners (Track 3) were supported by the Singapore Government through the Industry Alignment Fund—Industry Collaboration Projects Grant. This research was conducted at Singtel Cognitive and Artificial Intelligence Lab for Enterprises (SCALE@NTU), which is a collaboration between Singapore Telecommunications Limited (Singtel) and Nanyang Technological University (NTU). Team KawaguchiLab (Track 5) was supported by JSPS KAKENHI under Grant JP17H01762. Team WHU&AutoNavi (Track 6) was supported by the National Key Research and Development Program of China under Grant 2016YFB0502202. Team YAI (Tracks 6 and 7) was supported by the Ministry of Science and Technology (MOST) of Taiwan under Grant MOST 110-2634-F-155-001

Off-Line Evaluation of Indoor Positioning Systems in Different Scenarios: The Experiences From IPIN 2020 Competition

Every year, for ten years now, the IPIN competition has aimed at evaluating real-world indoor localisation systems by testing them in a realistic environment, with realistic movement, using the EvAAL framework. The competition provided a unique overview of the state-of-the-art of systems, technologies, and methods for indoor positioning and navigation purposes. Through fair comparison of the performance achieved by each system, the competition was able to identify the most promising approaches and to pinpoint the most critical working conditions. In 2020, the competition included 5 diverse off-site off-site Tracks, each resembling real use cases and challenges for indoor positioning. The results in terms of participation and accuracy of the proposed systems have been encouraging. The best performing competitors obtained a third quartile of error of 1 m for the Smartphone Track and 0.5 m for the Foot-mounted IMU Track. While not running on physical systems, but only as algorithms, these results represent impressive achievements.Track 3 organizers were supported by the European Union’s Horizon 2020 Research and Innovation programme under the Marie Skłodowska Curie Grant 813278 (A-WEAR: A network for dynamic WEarable Applications with pRivacy constraints), MICROCEBUS (MICINN, ref. RTI2018-095168-B-C55, MCIU/AEI/FEDER UE), INSIGNIA (MICINN ref. PTQ2018-009981), and REPNIN+ (MICINN, ref. TEC2017-90808-REDT). We would like to thanks the UJI’s Library managers and employees for their support while collecting the required datasets for Track 3. Track 5 organizers were supported by JST-OPERA Program, Japan, under Grant JPMJOP1612. Track 7 organizers were supported by the Bavarian Ministry for Economic Affairs, Infrastructure, Transport and Technology through the Center for Analytics-Data-Applications (ADA-Center) within the framework of “BAYERN DIGITAL II. ” Team UMinho (Track 3) was supported by FCT—Fundação para a Ciência e Tecnologia within the R&D Units Project Scope under Grant UIDB/00319/2020, and the Ph.D. Fellowship under Grant PD/BD/137401/2018. Team YAI (Track 3) was supported by the Ministry of Science and Technology (MOST) of Taiwan under Grant MOST 109-2221-E-197-026. Team Indora (Track 3) was supported in part by the Slovak Grant Agency, Ministry of Education and Academy of Science, Slovakia, under Grant 1/0177/21, and in part by the Slovak Research and Development Agency under Contract APVV-15-0091. Team TJU (Track 3) was supported in part by the National Natural Science Foundation of China under Grant 61771338 and in part by the Tianjin Research Funding under Grant 18ZXRHSY00190. Team Next-Newbie Reckoners (Track 3) were supported by the Singapore Government through the Industry Alignment Fund—Industry Collaboration Projects Grant. This research was conducted at Singtel Cognitive and Artificial Intelligence Lab for Enterprises (SCALE@NTU), which is a collaboration between Singapore Telecommunications Limited (Singtel) and Nanyang Technological University (NTU). Team KawaguchiLab (Track 5) was supported by JSPS KAKENHI under Grant JP17H01762. Team WHU&AutoNavi (Track 6) was supported by the National Key Research and Development Program of China under Grant 2016YFB0502202. Team YAI (Tracks 6 and 7) was supported by the Ministry of Science and Technology (MOST) of Taiwan under Grant MOST 110-2634-F-155-001.Peer reviewe

Floor number detection for smartphone-based pedestrian dead reckoning applications

We present a new floor number detection algorithm for use in smartphone-based indoor localisation systems. It is designed to complement any pedestrian dead reckoning (PDR) algorithm able to detect steps and estimate a 2D trajectory from data of the smartphone’s inertial measurement unit.Our proposed method is based on the Viterbi algorithm, fusing data from an off-the-shelf smartphone’s accelerometer, barometer and wifi received signal strength (RSS) measurements. The accelerometer is used to detect accelerating elevators, while the barometer is used to detect stair climbing. This is combined with model-based wifi RSS fingerprinting, enabling accurate floor number detection. Our system is tested in an office environment with 7 41 m x 27 m floors, each of which has 2 pre-existing wifi access points. The algorithm is evaluated with a total of 116 minutes of recorded data, in which the floor number changed 76 times and a distance of 4.8 km was travelled. Since the Viterbi algorithm allows to easily correct past states (i.e. floor numbers) based on new information, it is evaluated in real-time and batch mode. Our proposed algorithm achieves a floor number detection accuracy of 99.1% (real-time) and 99.7% (batch), while using only RSS measurements resulted in 91% accuracy

Multi-floor indoor pedestrian dead reckoning with a backtracking particle filter and viterbi-based floor number detection

We present a smartphone-based indoor localisation system, able to track pedestrians over multiple floors. The system uses Pedestrian Dead Reckoning (PDR), which exploits data from the smartphone's inertial measurement unit to estimate the trajectory. The PDR output is matched to a scaled floor plan and fused with model-based WiFi received signal strength fingerprinting by a Backtracking Particle Filter (BPF). We proposed a new Viterbi-based floor detection algorithm, which fuses data from the smartphone's accelerometer, barometer and WiFi RSS measurements to detect stairs and elevator usage and to estimate the correct floor number. We also proposed a clustering algorithm on top of the BPF to solve multimodality, a known problem with particle filters. The proposed system relies on only a few pre-existing access points, whereas most systems assume or require the presence of a dedicated localisation infrastructure. In most public buildings and offices, access points are often available at smaller densities than used for localisation. Our system was extensively tested in a real office environment with seven 41 m x 27 m floors, each of which had two WiFi access points. Our system was evaluated in real-time and batch mode, since the system was able to correct past states. The clustering algorithm reduced the median position error by 17% in real-time and 13% in batch mode, while the floor detection algorithm achieved a 99.1% and 99.7% floor number accuracy in real-time and batch mode, respectively

Using SAGE on COTS UWB signals for TOA estimation and body shadowing effect quantification

This work assesses the applicability of the well-known SAGE algorithm for time-of-arrival estimation on ultra-wideband (UWB) measurements taken with cheap COTS hardware. Performance is comparable with a simple leading-edge detection (LDE) algorithm, establishing a general precision of approximately 30 cm/60 cm. SAGE performance is slightly worse in general (33 cm/71 cm), but is more stable in non-line-of-sight (NLOS) caused by human body presence. A more detailed breakdown of the effect of incidence angle on one-dimensional ranging accuracy is studied in relationship to human body shadowing effects. Within a cone of 135 degrees in front of the UWB device (pointing away from the body), the azimuthal incidence angle has no influence on the ranging performance of either algorithm

Smartphone-based WiFi FTM fingerprinting approach with map-aided particle filter

Smartphone-based WiFi ranging positioning based on fine time measurement (FTM) always collapses in real-life scenarios. In this work, a novel map-aided particle filter (PF)-based WiFi FTM fingerprinting approach is proposed to address the poor performance of the WiFi FTM ranging positioning. Different from manually collecting fingerprints, this approach utilizes the theoretical received signal strength and geometric distances between the access points and reference points as the fingerprints, which means less labour-intensive work. For accurate WiFi position estimation, a map-aided PF is designed to find the optimal position. Extensive experiments are carried out in the non-line-of-sight (NLoS) and mixed line-of-sight/non-line-of-sight (LoS/NLoS) environments, and the testing results show that the accuracy and stability of FTM fingerprinting are improved by using the mixed RSS and ranging data fingerprints. The minimal mean location errors (MEs) of the PF-based WiFi FTM fingerprinting in NLoS and mixed LoS/NLoS conditions are 1.70 m and 1.85 m, respectively. Compared to the classic weighted least square method, the MEs are reduced by 54.91% and 45.43%, respectively. The testing results demonstrate that the PF-based FTM fingerprinting is an effective approach that provides satisfactory localization results in real-life indoor environments

IMU-aided detection and mitigation of human body shadowing for UWB positioning

Ultra-wideband (UWB) indoor positioning systems have the potential to achieve decimeter-level accuracy. However, the performance can degrade significantly under Non-Line-of-Sight (NLoS) conditions. Detection and mitigation of NLoS conditions is a complex problem, and has been the subject of many works over the past decades. When localizing pedestrians, human body shadowing (HBS) is an important cause of NLoS. In this paper, we propose an HBS mitigation strategy based on the orientation of the body and tag relative to the UWB anchors by attaching an inertial measurement unit to the UWB tag. Two algorithms are designed and implemented, of which the second algorithm is designed for robustness against errors in the IMU's estimated heading. The proposed algorithms are validated by UWB Two Way Ranging (TWR) measurements, performed in two environments. Two more algorithms are implemented as a benchmark, of which one is based on the estimated first path power, and the other is based on range residuals. The proposed algorithm outperforms the other algorithms in the higher error statistics, achieving a 49% reduction of the p90 error depending on the environment

Experimental benchmarking of next-gen indoor positioning technologies (unmodulated) visible light positioning and ultra-wideband

Within the context of the Internet of Things (IoT), many applications require high-quality positioning services. As opposed to traditional technologies, the two most recent positioning solutions: 1) ultra-wideband (UWB) and 2) (unmodulated) visible light positioning [(u)VLP] are well suited to economically supply centimeter-to-decimeter level accuracy. This manuscript benchmarks the 2-D positioning performance of an 8-anchor asymmetric double-sided two-way ranging (aSDS-TWR) UWB system and a 15-LED frequency-division multiple access (FDMA) received signal strength (RSS) (u)VLP system in terms of feasibility and accuracy. With extensive experimental data, collected at two heights in a 8 m by 6 m open zone equipped with a precise ground-truth system, it is demonstrated that both visible light positioning (VLP) and UWB already attain median and 90th percentile positioning errors in the order of 5 and 10 cm in line-of-sight (LOS) conditions. An approximately 20-cm median accuracy can be obtained with uVLP, whose main benefit is it being infrastructureless and thus very inexpensive. The accuracy degradation effects of non-LOS (NLOS) on UWB/(u)VLP are highlighted with four scenarios, each consisting of a different configuration of metallic closets. For the considered setup, in 2-D and with minimal tilt of the object to be tracked, VLP outscores UWB in NLOS conditions, while for LOS scenarios similar results are obtained

Les autres plantes à caoutchouc

Petites monographies au sujet de quatre plantes à caoutchouc dont 2 (guayule et maniçoba) font l'objet de recherche dans plusieurs pays et 2 (Kok-saghyz et Cryptostegia) dont les études ont été très poussées et même ont fait l'objet de cultures, mais qui, actuellement, ne sont plus d'actualit